Search Result

Search Results for " igg1 fc "

Targets

Compounds

Recombinant Proteins

Cat No.	Product Name	Synonyms	Targets
T76735	Mupadolimab	CPI-006	CD73
	Mupadolimab (CPI-006) is a humanized FC-γR binding deficient IgG1 anti-CD73 antibody with potential anticancer activity and activation of CD73POS B cells.		CD73
T76883	Talacotuzumab	CSL 362,JNJ 56022473	Immunology/Inflammation related , Interleukin
	Talacotuzumab (JNJ 56022473) is an IgG1 fully humanized CD123 neutralizing monoclonal antibody containing a modified Fc structure. Talacotuzumab has a high affinity for CD123, CD32b/c, CD16-158F and CD16-158V, with KD of...		Immunology/Inflammation related , Interleukin
T83063	Anti-IgG-Fc (Human)
	Anti-IgG-Fc (Human) is an antibody targeting the Fc region of human immunoglobulin G1 (IgG1) [1].
T77055	Lenercept
	Lenercept (Ro 45-2081) is a recombinant fusion protein combining the soluble TNF-receptor (p55) with the Fc portion of human IgG1 [1].
T76936	Budigalimab
	Budigalimab (ABBV 181; PR 1648817), a humanized IgG1 monoclonal antibody, specifically targets the programmed cell death 1 (PD-1) receptor. It features an Fc mutation to decrease interactions with the Fc receptor, thereb...
T76821	Ocaratuzumab
	Ocaratuzumab (AME 133v), an Fc-engineered humanized IgG1 anti-CD20 monoclonal antibody, demonstrates enhanced antibody-dependent cell-mediated cytotoxicity (ADCC) [1] [2] with a dissociation constant (Kd) of approximatel...
T77133	Prolgolimab
	Prolgolimab (BCD-100), a human IgG1 anti-PD-1 monoclonal antibody featuring the Fc-silencing 'LALA' mutation, is utilized in advanced melanoma research [1].
T78249	Nipocalimab	M281
	Nipocalimab (M281), a fully human, recombinant, aglycosylated IgG1 monoclonal antibody, exhibits high-affinity binding to the Fc receptor (FcRn) at both endosomal pH 6.0 and extracellular pH 7.6, characterized by its pic...
T76925	Benufutamab
	Benufutamab (GEN1029), a death receptor 5 (DR5)-specific agonistic antibody, comprises a blend of two non-competing DR5-specific IgG1 antibodies with an E430G mutation in the Fc domain. This compound exhibits antitumor e...
T77175	Efruxifermin
	Efruxifermin, an Fc-FGF21 fusion protein consisting of a human IgG1 Fc domain linked to modified human FGF21, exhibits a prolonged half-life and enhanced receptor affinity compared to its native counterpart. It is utiliz...
T77039	Ipafricept
	Ipafricept (OMP-54F28; FZD8-Fc), a pioneering recombinant fusion protein, incorporates the extracellular segment of the human frizzled-8 receptor and the Fc fragment of human IgG1, targeting the Wnt ligand. It exhibits a...
T10218	Abatacept	CTLA4lg	Others
	Abatacept (CTLA4lg) is a soluble fusion protein consisting of the extracellular domain of human CTLA4 and a fragment of the Fc portion of human IgG1 (hinge and CH2 and 3 domains). It is a selective T-cell co-stimulation ...		Others
T77061	Letolizumab
	Letolizumab (BMS-986004), a monoclonal antibody directed at CD40L, is engineered to express a mutant IgG1 devoid of effector functions, such as Fc binding and complement fixation. It effectively reduces rejection and thr...
T77906	Briobacept	BR 3FC
	Briobacept (BR 3FC), a selective human monoclonal antibody, targets BLyS (BAFF) to induce B-cell apoptosis and is a recombinant glycoprotein comprising two BLyS receptor (BR3) molecules fused to the Fc domain of human Ig...
T81605	Ontorpacept	TTI-621
	Ontorpacept (TTI-621) is a soluble fusion protein comprising the N-terminal (1-118) of human SIRPα fused to the Fc region of human IgG1. This N-terminal (1-118) segment serves as the binding domain for CD47, an inhibitor...
T76715	Envafolimab
	Envafolimab (ASC 22; KN 035), a recombinant humanized single-domain anti-PD-L1 antibody, integrates the anti-PD-L1 domain with the Fc fragment of the human IgG1 antibody. It inhibits the PD-L1 and PD-1 interaction with a...
T76716	Cadonilimab
	Cadonilimab (AK104) is a humanized antibody engineered from the IgG1 scaffold and targets PD1/CTLA4. It is utilized in the research of metastatic cervical cancer [1] [2].
T37005	Estriol 3-β-D-Glucuronide (sodium salt)
	Estriol 3-β-D-glucuronide is a metabolite of estriol . It is formed from estriol by the UDP-glucuronosyltransferase (UGT) isoform UGT1A10. Estriol 3-β-D-glucuronide binds to basolateral and canalicular liver plasma membr...
T76905	Anbenitamab
	Anbenitamab (KN-026) is a bispecific antibody that targets extracellular domains II and IV of human HER2, blocking both ligand-dependent and independent signaling pathways. Its IgG1 Fc fragment activates FcRγIIIa, trigge...

Compounds

Synonym: CSL 362,JNJ 56022473

Target: Immunology/Inflammation related, Interleukin

Anti-IgG-Fc (Human)

Estriol 3-β-D-Glucuronide (sodium salt)

Recombinant Proteins

Species：

Expression System：

Tag：

Cat No.	Product Name	Species	Expression System
TMPY-00820	IgG1 Fc Protein, Human, Recombinant (C103S)	Human	HEK293 Cells
	IgG1 Fc Protein, Human, Recombinant (C103S) is expressed in HEK293 mammalian cells. The predicted molecular weight is 26 kDa and the accession number is P01857-1.
TMPY-05138	IgG1 Fc Protein, Human, Recombinant (C103S), Biotinylated	Human	HEK293 Cells
	IgG1 Fc Protein, Human, Recombinant (C103S), Biotinylated is expressed in HEK293 mammalian cells. The predicted molecular weight is 26.1 kDa and the accession number is AAC82527.1.
TMPY-06893	IgG1 Fc Protein, Human, Recombinant (C103S, Avi), Biotinylated	Human	HEK293 Cells
	IgG1 Fc Protein, Human, Recombinant (C103S, Avi), Biotinylated is expressed in HEK293 mammalian cells. The predicted molecular weight is 27.89 kDa and the accession number is AAC82527.1.
TMPK-00759	IgG1 Fc Protein, Human, Recombinant	Human	HEK293 Cells
	IgG1 is most abundant in serum among the four IgG subclasses (IgG1, 2, 3 and 4) and binds to Fc receptors (FcγR) on phagocytic cells with high affinity. Fc fragment is demonstrated to mediate phagocytosis, trigger inflam...
TMPK-00760	IgG1 Fc Protein, Mouse, Recombinant	Mouse	HEK293 Cells
	Recombinant murine Fc fragment contains the hinge region, CH2, and CH3 region of the mouse IgG1 isotype. IgG1 is most abundant in serum among the four IgG subclasses (IgG1, 2, 3 and 4) and binds to Fc receptors (FcγR) on...
TMPY-06605	IgG1 Fc Protein, Mouse, Recombinant (C102S)	Mouse	HEK293 Cells
	IgG1 Fc Protein, Mouse, Recombinant (C102S) is expressed in HEK293 mammalian cells. The predicted molecular weight is 25.8 kDa and the accession number is AAK53870.1.
TMPY-00105	Recombinant Protein G		E. coli
	Protein G is a bacterial cell wall protein expressed at the cell surface of certain group C and group G Streptococcal strains. It has affinity for both Fab- and Fc-fragments of human IgG by independent and separate bindi...
TMPY-05037	CD3E & CD3G Heterodimer Protein, Mouse, Recombinant (hFc & His)	Mouse	HEK293 Cells
	CD3E & CD3G Heterodimer Protein, Mouse, Recombinant (C-human IgG1-Fc & His & C-human IgG1-Fc) is expressed in HEK293 mammalian cells. The predicted molecular weight is 75.4 kDa and the accession number is NP_031674.1&NP_...
TMPK-01115	Fc gamma RIII/CD16 Protein, Cynomolgus, Recombinant (His)	Cynomolgus	HEK293 Cells
	Immunoglobulin G (IgG) Fc receptors play a critical role in linking IgG antibody-mediated immune responses with cellular effector functions. A high resolution map of the binding site on human IgG1 for human Fc gamma RI, ...
TMPK-00641	IgG2C Protein, Mouse, Recombinant	Mouse	HEK293 Cells
	Mouse IgG2c is a subclass of mouse antibody IgG, it can bind FcγRIV with high affinity and the Fc loop residues of mouse IgG2c promote greater receptor-binding affinity than mouse IgG2b or human IgG1.
TMPJ-00751	IgG4 hFc Protein, Human, Recombinant (aa 99-326)	Human	HEK293 Cells
	As a monomeric immunoglobulin that is predominately involved in the secondary antibody response and the only isotype that can pass through the human placenta, Immunoglobulin G (IgG) is synthesized and secreted by plasma ...
TMPY-04964	Recombinant Protein A, HRP conjugate
	Protein A is surface protein originally found in the cell wall of the bacteria Staphylococcusaureus. It is encoded by the spa gene and its regulation is controlled by DNA topology, cellular osmolarity, and a two componen...
TMPJ-00597	IgG1 hFc Protein, Mouse, Recombinant	Mouse	HEK293 Cells
	As a monomeric immunoglobulin that is predominately involved in the secondary antibody response and the only isotype that can pass through the human placenta, Immunoglobulin G (IgG) is synthesized and secreted by plasma ...